Search results for " pyranocoumarins"

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Antimicrobial and Antioxidant Activities of Coumarins from the Roots of Ferulago campestris (Apiaceae)

2009

We report the isolation of several coumarins and the stereochemical assessment of some pyranocoumarins, as well as the antibacterial and antioxidant activities of the three most abundant ones (grandivittin, agasyllin and aegelinol benzoate) isolated from the roots of Ferulago campestris collected in Sicily and of the hydrolysis product (aegelinol). Aegelinol and agasyllin showed antibacterial activity against nine ATCC and the same clinically isolated Gram-positive and Gram-negative bacterial strains. At a concentration between 16 and 125 μg/mL both coumarins showed a significant antibacterial effect against both Gram-negative and Gram-positive bacteria. In particular the ATCC strains Staph…

food.ingredientNeutrophilsPharmaceutical ScienceBiologyGram-Positive Bacteriamedicine.disease_causePlant RootsPyranocoumarinsPyranocoumarinsAntioxidantsArticleAnalytical ChemistryFerulagoMicrobiologyfoodAnti-Infective AgentsAntioxidant activityCoumarinsGram-Negative BacteriaDrug DiscoveryLeukocytesmedicineHumansAbsolute configurationPhysical and Theoretical ChemistryFerulago campestris coumarins pyranocoumarins absolute configuration antibacterial activity antioxidant activityDose-Response Relationship DrugOrganic ChemistrySettore CHIM/06 - Chimica OrganicaEnterobacterbiology.organism_classificationAntimicrobialChemistry (miscellaneous)Staphylococcus aureusMolecular MedicineFerulago campestris; Coumarins; Pyranocoumarins; Absolute configuration; Antibacterial activity; Antioxidant activityFerulago campestrisAntibacterial activityAntibacterial activityEnterobacter cloacaeBacteriaApiaceaeMolecules; Volume 14; Issue 3; Pages: 939-952
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